One more thing that is signficant (well, I think it is) --
Let the base of the nose just be the base, in shadow. Don't let a lot of light get in there to, say, define the structure around the nostril, and don't let the nostril value be a lot darker than the shadow area. Kind of take the shadow shape under the nose in the posterization on the right (that is, of the reference photo) as a guide. Within that shape is very little effort to pull out lights, and it isn't necessary anyway. Viewers know what the structure of the nose is, and they know about shadows, so their eyes will supply the detail. You don't need to, and in fact by doing so, those elements say "Look at me!", which isn't what you want to have happening in that area.
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