Generally speaking, flake white is a faster dryer than are the other whites. Grumbacher's very stiff flake white still dries reasonably quickly with the additon of a softer white. I use Permelba for this. I also use Permelba by itself, and like it.
I also premix some of my colors in strings, going from dark to light. While making the string, I add a drop or two of Liquin as I go along. The result is a very touch dry painting the following day.
The difference (in color) between the flakes and Permelba is that the flakes tend to be a little warmer.
I've also used the dreaded cobalt dryers, and my experience is that you have to use them like I use Liquin -- very little. Cobalt, like Liquin, dries quite well, and usually overnight.
Over the years, I have quit fiddling with these various whites and find myself using mostly Permelba.
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